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In Vivo Selection of a Lymphocytic Choriomeningitis Virus Variant That Affects Recognition of the GP33-43 Epitope by H-2D(b) but Not H-2K(b)

CD8 T cells drive the protective immune response to lymphocytic choriomeningitis virus (LCMV) infection and are thus a determining force in the selection of viral variants. To examine how escape mutations affect the presentation and recognition of overlapping T-cell epitopes, we isolated an LCMV var...

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Detalhes bibliográficos
Main Authors: Puglielli, Maryann T., Zajac, Allan J., van der Most, Robbert G., Dzuris, John L., Sette, Alessandro, Altman, John D., Ahmed, Rafi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114915/
https://ncbi.nlm.nih.gov/pubmed/11333891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.11.5099-5107.2001
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