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Beta-lactamase inhibitors. The inhibition of serine beta-lactamases by specific boronic acids.

Many beta-lactamases have active-site serine residues, and are competitively inhibited by boronic acids. Hitherto, the boronic acids used have lacked any structural resemblance to the substrates of beta-lactamases. Phenylacetamidomethaneboronic acid, trifluoroacetamidomethaneboronic acid and 2,6-dim...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Crompton, I E, Cuthbert, B K, Lowe, G, Waley, S G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1988
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149024/
https://ncbi.nlm.nih.gov/pubmed/3135799
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