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Insulin and glucagon attenuate the ability of cholera toxin to activate adenylate cyclase in intact hepatocytes.

Treatment of intact hepatocytes with cholera toxin at 37 degrees C caused a stable activation of adenylate cyclase activity after a lag period of around 10 min. The presence of either insulin (10 nM) or glucagon (10 nM) in the incubation medium had little effect on this lag period; however, these ho...

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Библиографические подробности
Главные авторы: Irvine, F J, Houslay, M D
Формат: Artigo
Язык:Inglês
Опубликовано: 1988
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149023/
https://ncbi.nlm.nih.gov/pubmed/2840894
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