Suboptimal Nucleotides in the Infectious, Pathogenic Simian Immunodeficiency Virus Clone SIVmac239

We analyzed virus sequences in two monkeys infected with SIVmac239 and two monkeys infected with SHIVnef that maintained high, persisting viral loads. Sequence changes were observed consistently at four loci in all four animals: a single nucleotide change in the Lys-tRNA primer binding site in the 5...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Alexander, Louis, Denekamp, Lynn, Czajak, Susan, Desrosiers, Ronald C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114897/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11264395/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.8.4019-4022.2001
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