Suboptimal Nucleotides in the Infectious, Pathogenic Simian Immunodeficiency Virus Clone SIVmac239

We analyzed virus sequences in two monkeys infected with SIVmac239 and two monkeys infected with SHIVnef that maintained high, persisting viral loads. Sequence changes were observed consistently at four loci in all four animals: a single nucleotide change in the Lys-tRNA primer binding site in the 5...

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Pubblicato in:	J Virol
Autori principali:	Alexander, Louis, Denekamp, Lynn, Czajak, Susan, Desrosiers, Ronald C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114897/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11264395/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.8.4019-4022.2001
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