Human Immunodeficiency Virus Type 1 Particles Pseudotyped with Envelope Proteins That Fuse at Low pH No Longer Require Nef for Optimal Infectivity

We have investigated the effects of Nef on infectivity in the context of various viral envelope proteins. These experiments were performed with a minimal vector system where Nef is the only accessory protein present. Our results support the hypothesis that the route of entry influences the ability o...

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Hlavní autoři: Chazal, Nathalie, Singer, Gregory, Aiken, Christopher, Hammarskjöld, Marie-Louise, Rekosh, David
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC114896/
https://ncbi.nlm.nih.gov/pubmed/11264394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.8.4014-4018.2001
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