Propagation of Rat Parvovirus in Thymic Lymphoma Cell Line C58(NT)D and Subsequent Appearance of a Resistant Cell Clone after Lytic Infection

Rat parvovirus (RPV) is nonpathogenic in rats but causes persistent lymphocytotropic infection. We found that RPV was propagated in rat thymic lymphoma cell line C58(NT)D and induced apoptosis. Interestingly, a resistant subclone, C58(NT)D/R, from surviving cells after lytic infection had differenti...

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Bibliographic Details
Main Authors: Ueno, Yutaka, Harada, Tanenobu, Iseki, Hiroyoshi, Ohshima, Takayuki, Sugiyama, Fumihiro, Yagami, Ken-ichi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114887/
https://ncbi.nlm.nih.gov/pubmed/11264385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.8.3965-3970.2001
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