Role of Alpha/Beta Interferon in Venezuelan Equine Encephalitis Virus Pathogenesis: Effect of an Attenuating Mutation in the 5′ Untranslated Region

Venezuelan equine encephalitis virus (VEE) is an important equine and human pathogen of the Americas. In the adult mouse model, cDNA-derived, virulent V3000 inoculated subcutaneously (s.c.) causes high-titer peripheral replication followed by neuroinvasion and lethal encephalitis. A single change (G...

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Hlavní autoři: White, Laura J., Wang, Jia-Gang, Davis, Nancy L., Johnston, Robert E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC114862/
https://ncbi.nlm.nih.gov/pubmed/11264360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.8.3706-3718.2001
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