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Role of Alpha/Beta Interferon in Venezuelan Equine Encephalitis Virus Pathogenesis: Effect of an Attenuating Mutation in the 5′ Untranslated Region

Venezuelan equine encephalitis virus (VEE) is an important equine and human pathogen of the Americas. In the adult mouse model, cDNA-derived, virulent V3000 inoculated subcutaneously (s.c.) causes high-titer peripheral replication followed by neuroinvasion and lethal encephalitis. A single change (G...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: White, Laura J., Wang, Jia-Gang, Davis, Nancy L., Johnston, Robert E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114862/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11264360/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.8.3706-3718.2001
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