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Reagents for reversible coupling of proteins to the active centres of trypsin-like serine proteinases.

In order to extend the scope for the application of acyl-enzymes as fibrinolytic agents, p-amidinophenyl ester enzyme substrates were prepared that gave stabilized acyl-enzymes capable of being coupled to other proteins. Coupling was achieved by reaction of protein thiol functions with a 2-pyridyldi...

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Autores principales: Kalindjian, S B, Smith, R A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1987
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1148556/
https://ncbi.nlm.nih.gov/pubmed/2963619
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