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Histidine sequences in the active centres of some `serine' proteinases

1. A comparison of the diagonal `maps' of chymotrypsin A and `tosylphenylalanyl chloromethyl ketone'-inhibited chymotrypsin A showed that His-57 is alkylated specifically by this substrate analogue. 2. From peptic digests of chymotrypsinogen A and B, trypsin and elastase it was demonstrate...

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Bibliographic Details
Main Authors: Smillie, L. B., Hartley, B. S.
Format: Artigo
Language:Inglês
Published: 1966
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1270088/
https://ncbi.nlm.nih.gov/pubmed/5971785
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