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Characterization of the CD154-Positive and CD40-Positive Cellular Subsets Required for Pathogenesis in Retrovirus-Induced Murine Immunodeficiency

Genetically susceptible C57BL/6 (B6) mice that are infected with the LP-BM5 isolate of murine retroviruses develop profound splenomegaly, lymphadenopathy, hypergammaglobulinemia, terminal B-cell lymphomas, and an immunodeficiency state bearing many similarities to the pathologies seen in AIDS. Becau...

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Detalhes bibliográficos
Main Authors: Green, Kathy A., Noelle, Randolph J., Durell, Brigit G., Green, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114849/
https://ncbi.nlm.nih.gov/pubmed/11264347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.8.3581-3589.2001
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