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Latently Expressed Human Herpesvirus 8-Encoded Interferon Regulatory Factor 2 Inhibits Double-Stranded RNA-Activated Protein Kinase

Human herpesvirus 8 (HHV-8; Kaposi's sarcoma herpesvirus) encodes four open reading frames with homology to cellular proteins of interferon regulatory factor (IRF) family. Three of them, viral IRF-1 (vIRF-1), vIRF-2, and vIRF-3, have been cloned and found, when overexpressed, to down-regulate t...

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Detalhes bibliográficos
Main Authors: Buryýšek, Ladislav, Pitha, Paula M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114818/
https://ncbi.nlm.nih.gov/pubmed/11160738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.5.2345-2352.2001
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