Regulation of DNA-Raised Immune Responses by Cotransfected Interferon Regulatory Factors

Interferon regulatory factor 1 (IRF-1), IRF-3, and IRF-7 have been tested as genetic adjuvants for influenza virus hemagglutinin (HA) and nucleoprotein vaccine DNAs. Cotransfection of HA with IRF-3 and IRF-7 increased CD4 T-cell responses by 2- to 4-fold and CD8 T-cell responses by more than 10-fold...

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Vydáno v:	J Virol
Hlavní autoři:	Sasaki, Shin, Amara, Rama Rao, Yeow, Wen-Shuz, Pitha, Paula M., Robinson, Harriet L.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2002
Témata:	Vaccines and Antiviral Agents
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136278/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12050378/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.13.6652-6659.2002
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