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The preparation of monoclonal antibodies to human bone and liver alkaline phosphatase and their use in immunoaffinity purification and in studying these enzymes when present in serum.

1. Liver and bone alkaline phosphatase isoenzymes were solubilized with the zwitterionic detergent sulphobetaine 14, and purified to homogeneity by using a monoclonal antibody previously raised against a partially-purified preparation of the liver isoenzyme. Both purified isoenzymes had a specific a...

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Detalhes bibliográficos
Main Authors: Bailyes, E M, Seabrook, R N, Calvin, J, Maguire, G A, Price, C P, Siddle, K, Luzio, J P
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1148056/
https://ncbi.nlm.nih.gov/pubmed/2451502
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