Vaccinia Virus Infection Disarms the Mitochondrion-Mediated Pathway of the Apoptotic Cascade by Modulating the Permeability Transition Pore

Many viruses have evolved strategies that target crucial components within the apoptotic cascade. One of the best studied is the caspase 8 inhibitor, crmA/Spi-2, encoded by members of the poxvirus family. Since many proapoptotic stimuli induce apoptosis through a mitochondrion-dependent, caspase 8-i...

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Bibliographic Details
Main Authors: Wasilenko, Shawn T., Meyers, Adrienne F. A., Vander Helm, Kathleen, Barry, Michele
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114730/
https://ncbi.nlm.nih.gov/pubmed/11689625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.23.11437-11448.2001
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