Vaccinia Virus Infection Disarms the Mitochondrion-Mediated Pathway of the Apoptotic Cascade by Modulating the Permeability Transition Pore

Many viruses have evolved strategies that target crucial components within the apoptotic cascade. One of the best studied is the caspase 8 inhibitor, crmA/Spi-2, encoded by members of the poxvirus family. Since many proapoptotic stimuli induce apoptosis through a mitochondrion-dependent, caspase 8-i...

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Detalhes bibliográficos
Main Authors: Wasilenko, Shawn T., Meyers, Adrienne F. A., Vander Helm, Kathleen, Barry, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114730/
https://ncbi.nlm.nih.gov/pubmed/11689625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.23.11437-11448.2001
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