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Monoclonal antibodies to the guanine-nucleotide binding proteins of adenylate cyclase.

Monoclonal antibodies (Mabs) to the stimulatory (Ns) and inhibitory (Ni) guanine nucleotide regulatory proteins associated with adenylate cyclase have been developed. Two Mabs (2A3 and 5G12), which are of the IgG2b subclass, recognize the beta-subunits (beta) of Ns, Ni and transducin. Iodinated beta...

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Bibliographic Details
Main Authors: Lingham, R B, Brown, P J, Holcombe, V, Schreiber, C L
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1146815/
https://ncbi.nlm.nih.gov/pubmed/3098233
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