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Neuroadapted Yellow Fever Virus 17D: Genetic and Biological Characterization of a Highly Mouse-Neurovirulent Virus and Its Infectious Molecular Clone

A neuroadapted strain of yellow fever virus (YFV) 17D derived from a multiply mouse brain-passaged virus (Porterfield YF17D) was additionally passaged in SCID and normal mice. The virulence properties of this virus (SPYF) could be distinguished from nonneuroadapted virus (YF5.2iv, 17D infectious clo...

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Bibliografiske detaljer
Main Authors: Chambers, Thomas J., Nickells, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC114671/
https://ncbi.nlm.nih.gov/pubmed/11602731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.22.10912-10922.2001
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