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Effects of monensin on insulin interactions with isolated hepatocytes. Evidence for inhibition of receptor recycling and insulin degradation.

Recent evidence suggests that, during endocytosis, receptors for many polypeptide ligands are spared degradation and are recycled to the plasma membrane for re-utilization. The univalent ionophore monensin was shown to inhibit membrane recycling. We therefore examined its effects on insulin interact...

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Sonraí Bibleagrafaíochta
Main Authors: Whittaker, J, Hammond, V A, Taylor, R, Alberti, K G
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1986
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1146588/
https://ncbi.nlm.nih.gov/pubmed/3521587
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