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Induction of Rapid and Extensive β-Chemokine Synthesis in Macrophages by Human Immunodeficiency Virus Type 1 and gp120, Independently of Their Coreceptor Phenotype

Human immunodeficiency virus type 1 (HIV-1) interacts with its target cells through CD4 and a coreceptor, generally CCR5 or CXCR4. Macrophages display CD4, CCR5, and CXCR4 that are competent for binding and entry of virus. Virus binding also induces several responses by lymphocytes and macrophages t...

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Autori principali: Choe, Wonkyu, Volsky, David J., Potash, Mary Jane
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC114655/
https://ncbi.nlm.nih.gov/pubmed/11602715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.22.10738-10745.2001
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