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Isolation and Characterization of Noncytopathic Pestivirus Mutants Reveals a Role for Nonstructural Protein NS4B in Viral Cytopathogenicity

Isolates of bovine viral diarrhea virus (BVDV), the prototype pestivirus, are divided into cytopathic (cp) and noncytopathic (ncp) biotypes according to their effect on cultured cells. The cp viruses also differ from ncp viruses by the production of viral nonstructural protein NS3. However, the mech...

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Autors principals: Qu, Lin, McMullan, Laura K., Rice, Charles M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114647/
https://ncbi.nlm.nih.gov/pubmed/11602707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.22.10651-10662.2001
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