Isolation and Characterization of Noncytopathic Pestivirus Mutants Reveals a Role for Nonstructural Protein NS4B in Viral Cytopathogenicity

Isolates of bovine viral diarrhea virus (BVDV), the prototype pestivirus, are divided into cytopathic (cp) and noncytopathic (ncp) biotypes according to their effect on cultured cells. The cp viruses also differ from ncp viruses by the production of viral nonstructural protein NS3. However, the mech...

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Bibliographic Details
Main Authors: Qu, Lin, McMullan, Laura K., Rice, Charles M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114647/
https://ncbi.nlm.nih.gov/pubmed/11602707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.22.10651-10662.2001
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