An Attenuating Mutation in the 2A Protease of Swine Vesicular Disease Virus, a Picornavirus, Regulates Cap- and Internal Ribosome Entry Site-Dependent Protein Synthesis

Virulent and avirulent strains of swine vesicular disease virus (SVDV), a picornavirus, have been characterized previously. The major determinants for attenuation have been mapped to specific residues in the 1D-2A-coding region. The properties of the 2A proteases from the virulent and avirulent stra...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Sakoda, Yoshihiro, Ross-Smith, Natalie, Inoue, Toru, Belsham, Graham J.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2001
Fag:	Virus-Cell Interactions
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114646/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11602706/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.22.10643-10650.2001
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