Human Cytomegalovirus Protein US2 Interferes with the Expression of Human HFE, a Nonclassical Class I Major Histocompatibility Complex Molecule That Regulates Iron Homeostasis

HFE is a nonclassical class I major histocompatibility complex (MHC) molecule that is mutated in the autosomal recessive iron overload disease hereditary hemochromatosis. There is evidence linking HFE with reduced iron uptake by the transferrin receptor (TfR). Using a panel of HFE and TfR monoclonal...

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Bibliographic Details
Main Authors: Ben-Arieh, Sayeh Vahdati, Zimerman, Baruch, Smorodinsky, Nechama I., Yaacubovicz, Margalit, Schechter, Chana, Bacik, Igor, Gibbs, Jim, Bennink, Jack R., Yewdell, Jon W., Coligan, John E., Firat, Hüseyin, Lemonnier, François, Ehrlich, Rachel
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114637/
https://ncbi.nlm.nih.gov/pubmed/11581431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.21.10557-10562.2001
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