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Cellular Membrane-Binding Ability of the C-Terminal Cytoplasmic Domain of Human Immunodeficiency Virus Type 1 Envelope Transmembrane Protein gp41

The amphipathic α-helices located in the cytoplasmic tail of the envelope (Env) transmembrane glycoprotein gp41 of human immunodeficiency virus type 1 have been implicated in membrane association and cytopathicity. Deletion of the last 12 amino acids in the C terminus of this domain severely impairs...

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Autors principals: Chen, Steve S.-L., Lee, Sheau-Fen, Wang, Chin-Tien
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114564/
https://ncbi.nlm.nih.gov/pubmed/11559825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.20.9925-9938.2001
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