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Virion incorporation of envelope glycoproteins with long but not short cytoplasmic tails is blocked by specific, single amino acid substitutions in the human immunodeficiency virus type 1 matrix.

Incorporation of envelope glycoproteins into a budding retrovirus is an essential step in the formation of an infectious virus particle. By using site-directed mutagenesis, we identified specific amino acid residues in the matrix domain of the human immunodeficiency virus type 1 (HIV-1) Gag protein...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Freed, E O, Martin, M A
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188822/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7853546/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.3.1984-1989.1995
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