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Alternative Mechanisms of Respiratory Syncytial Virus Clearance in Perforin Knockout Mice Lead to Enhanced Disease

Virus-specific cytotoxic T lymphocytes are key effectors for the clearance of virus-infected cells and are required for the normal clearance of respiratory syncytial virus (RSV) in mice. Although perforin/granzyme-mediated lysis of infected cells is thought to be the major molecular mechanism used b...

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Detalhes bibliográficos
Main Authors: Aung, Sandra, Rutigliano, John A., Graham, Barney S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114563/
https://ncbi.nlm.nih.gov/pubmed/11559824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.20.9918-9924.2001
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