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Alternative Mechanisms of Respiratory Syncytial Virus Clearance in Perforin Knockout Mice Lead to Enhanced Disease

Virus-specific cytotoxic T lymphocytes are key effectors for the clearance of virus-infected cells and are required for the normal clearance of respiratory syncytial virus (RSV) in mice. Although perforin/granzyme-mediated lysis of infected cells is thought to be the major molecular mechanism used b...

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Udgivet i:J Virol
Principais autores: Aung, Sandra, Rutigliano, John A., Graham, Barney S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114563/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11559824/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.20.9918-9924.2001
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