Interleukin-12- and Gamma Interferon-Dependent Innate Immunity Are Essential and Sufficient for Long-Term Survival of Passively Immunized Mice Infected with Herpes Simplex Virus Type 1

Interferon (IFN) type I (alpha/beta IFN [IFN-α/β]) is very important in directly controlling herpes simplex virus type I (HSV-1) replication as well as in guiding and upregulating specific immunity against this virus. By contrast, the roles of IFN type II (IFN-γ) and antibodies in the defense agains...

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Detalhes bibliográficos
Main Authors: Vollstedt, Sabine, Franchini, Marco, Alber, Gottfried, Ackermann, Mathias, Suter, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114530/
https://ncbi.nlm.nih.gov/pubmed/11559791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.20.9596-9600.2001
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