Interaction of Classical Swine Fever Virus with Membrane-Associated Heparan Sulfate: Role for Virus Replication In Vivo and Virulence

Passage of native classical swine fever virus (CSFV) in cultured swine kidney cells (SK6 cells) selects virus variants that attach to the surface of cells by interaction with membrane-associated heparan sulfate (HS). A Ser-to-Arg change in the C terminus of envelope glycoprotein E(rns) (amino acid 4...

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Detalhes bibliográficos
Main Authors: Hulst, M. M., van Gennip, H. G. P., Vlot, A. C., Schooten, E., de Smit, A. J., Moormann, R. J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114529/
https://ncbi.nlm.nih.gov/pubmed/11559790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.20.9585-9595.2001
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