Carnitine prevents the early mitochondrial damage induced by methylglyoxal bis(guanylhydrazone) in L1210 leukaemia cells.

We previously found that the anti-cancer drug methylglyoxal bis(guanylhydrazone) (mitoguazone) depresses carnitine-dependent oxidation of long-chain fatty acids in cultured mouse leukaemia cells [Nikula, Alhonen-Hongisto, Seppänen & Jänne (1984) Biochem. Biophys. Res. Commun. 120, 9-14]. We have...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Nikula, P, Ruohola, H, Alhonen-Hongisto, L, Jänne, J
Format: Artigo
Langue:Inglês
Publié: 1985
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1145010/
https://ncbi.nlm.nih.gov/pubmed/3837667
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