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Induction of p53-Independent Apoptosis by Simian Virus 40 Small t Antigen

Simian virus 40 small t antigen (st) is required for optimal transformation and replication properties of the virus. We find that in certain cell types, such as the human osteosarcoma cell line U2OS, st is capable of inducing apoptosis, as evidenced by a fragmented nuclear morphology and positive te...

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Detalles Bibliográficos
Main Authors: Gjoerup, Ole, Zaveri, Darshana, Roberts, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC114483/
https://ncbi.nlm.nih.gov/pubmed/11533178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.19.9142-9155.2001
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