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Receptor Binding Transforms the Surface Subunit of the Mammalian C-Type Retrovirus Envelope Protein from an Inhibitor to an Activator of Fusion

The envelope protein (Env) of murine leukemia viruses (MLVs) is composed of a surface subunit (SU) and a transmembrane subunit (TM), which mediates membrane fusion, resulting in infection. SU contains a discrete N-terminal receptor binding domain (RBD) that is connected to the remainder of Env by a...

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Detalhes bibliográficos
Main Authors: Barnett, Anna L., Cunningham, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114478/
https://ncbi.nlm.nih.gov/pubmed/11533173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.19.9096-9105.2001
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