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Substitutions in the Receptor-Binding Domain of the Avian Sarcoma and Leukosis Virus Envelope Uncouple Receptor-Triggered Structural Rearrangements in the Surface and Transmembrane Subunits
The retrovirus avian sarcoma and leukosis virus (ASLV) enters cells via pH-independent membrane fusion. This reaction is catalyzed by the viral glycoprotein Env, composed of a membrane-distal subunit, SU, and a membrane-anchored subunit, TM. Previous mutational analysis of a variable region, central...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC104069/ https://ncbi.nlm.nih.gov/pubmed/10074159 |
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