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Substitutions in the Receptor-Binding Domain of the Avian Sarcoma and Leukosis Virus Envelope Uncouple Receptor-Triggered Structural Rearrangements in the Surface and Transmembrane Subunits

The retrovirus avian sarcoma and leukosis virus (ASLV) enters cells via pH-independent membrane fusion. This reaction is catalyzed by the viral glycoprotein Env, composed of a membrane-distal subunit, SU, and a membrane-anchored subunit, TM. Previous mutational analysis of a variable region, central...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Damico, Rachel, Rong, Lijun, Bates, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1999
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104069/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10074159/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.4.3087-3094.1999
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