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Substitutions in the Receptor-Binding Domain of the Avian Sarcoma and Leukosis Virus Envelope Uncouple Receptor-Triggered Structural Rearrangements in the Surface and Transmembrane Subunits

The retrovirus avian sarcoma and leukosis virus (ASLV) enters cells via pH-independent membrane fusion. This reaction is catalyzed by the viral glycoprotein Env, composed of a membrane-distal subunit, SU, and a membrane-anchored subunit, TM. Previous mutational analysis of a variable region, central...

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Hlavní autoři: Damico, Rachel, Rong, Lijun, Bates, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC104069/
https://ncbi.nlm.nih.gov/pubmed/10074159
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