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Inhibitors of angiotensin-converting enzyme containing a tetrahedral arsenic atom.

A series of tetrahedral oxo acids of Group VA and VIA elements and of silicon and boron were examined as inhibitors of angiotensin-converting enzyme. Arsenate is a competitive inhibitor with a Ki of 27 +/- 1 mM, at least 10-fold more potent than phosphate. Dimethylarsinate is a competitive inhibitor...

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Библиографические подробности
Главные авторы: Galardy, R E, Kortylewicz, Z P
Формат: Artigo
Язык:Inglês
Опубликовано: 1985
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1144731/
https://ncbi.nlm.nih.gov/pubmed/2986596
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