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Soluble C3 proconvertase and convertase of the classical pathway of human complement. Conditions of stabilization in vitro.

Soluble classical-pathway C3 convertase and proconvertase were prepared from purified C4b-C2ox complex in the presence of Ni2+; the two complexes, stable for at least 15 h at 4 degrees C, were isolated by sucrose-density-gradient ultracentrifugation. The C3 convertase alone was able to cleave C3, an...

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Dettagli Bibliografici
Autori principali: Villiers, M B, Thielens, N M, Colomb, M G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1985
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1144729/
https://ncbi.nlm.nih.gov/pubmed/3922352
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