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Intracellular DNA damage produced by a series of diacridines.

The intracellular DNA damage produced by a series of diacridines after a 2 h pulse treatment of L1210 cells in culture was investigated by using the alkaline-elution technique. Like other intercalating agents, diacridines produce single-strand breaks and protein-DNA links. There is a large increase...

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Detalhes bibliográficos
Main Authors: Roos, I A, Wakelin, L P, Henry, S J
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1144690/
https://ncbi.nlm.nih.gov/pubmed/3977863
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