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Mechanism of depolarization of rat cortical synaptosomes at submicromolar external Ca2+ activity. The use of Ca2+ buffers to control the synaptosomal membrane potential.

Rat cortical synaptosomes responded to a reduction of external Ca2+ from pCa 3.5 to pCa 4.8 in the absence of MgCl2 with a slight decrease of internal K+ and an increase of Na+. The effects were prevented by tetrodotoxin or millimolar concentrations of MgCl2. Further lowering of external pCa to 7.7...

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Detalhes bibliográficos
Autor principal: Schmalzing, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1144643/
https://ncbi.nlm.nih.gov/pubmed/3977854
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