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Depolarization-induced release of propranolol and atenolol from rat cortical synaptosomes.

The accumulation and release of [3H]-propranolol and [3H]-atenolol were examined in synaptosomes from rat cerebral cortex. Synaptosomes accumulated 20 pmol propranolol and 0.6 pmol atenolol mg-1 protein when incubated at 30 degrees C with radiolabelled drugs (0.1 microM). Exposure of propranolol-loa...

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Bibliografische gegevens
Hoofdauteurs: Bright, P. S., Gaffney, T. E., Street, J. A., Webb, J. G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1985
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987298/
https://ncbi.nlm.nih.gov/pubmed/3919793
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