Adenovirus Type 9 Fiber Knob Binds to the Coxsackie B Virus-Adenovirus Receptor (CAR) with Lower Affinity than Fiber Knobs of Other CAR-Binding Adenovirus Serotypes

The coxsackie B virus and adenovirus (Ad) receptor (CAR) functions as an attachment receptor for multiple Ad serotypes. Here we show that the Ad serotype 9 (Ad9) fiber knob binds to CAR with much reduced affinity compared to the binding by Ad5 and Ad12 fiber knobs as well as the knob of the long fib...

Full description

Saved in:
Bibliographic Details
Main Authors: Kirby, Ian, Lord, Rosemary, Davison, Elizabeth, Wickham, Thomas J., Roelvink, Peter W., Kovesdi, Imre, Sutton, Brian J., Santis, George
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114453/
https://ncbi.nlm.nih.gov/pubmed/11435605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.15.7210-7214.2001
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items