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Adenovirus Type 9 Fiber Knob Binds to the Coxsackie B Virus-Adenovirus Receptor (CAR) with Lower Affinity than Fiber Knobs of Other CAR-Binding Adenovirus Serotypes

The coxsackie B virus and adenovirus (Ad) receptor (CAR) functions as an attachment receptor for multiple Ad serotypes. Here we show that the Ad serotype 9 (Ad9) fiber knob binds to CAR with much reduced affinity compared to the binding by Ad5 and Ad12 fiber knobs as well as the knob of the long fib...

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Published in:J Virol
Main Authors: Kirby, Ian, Lord, Rosemary, Davison, Elizabeth, Wickham, Thomas J., Roelvink, Peter W., Kovesdi, Imre, Sutton, Brian J., Santis, George
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2001
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114453/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11435605/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.15.7210-7214.2001
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