Functional Interaction between Fluorodeoxyuridine-Induced Cellular Alterations and Replication of a Ribonucleotide Reductase-Negative Herpes Simplex Virus

G207 is an oncolytic herpes simplex virus (HSV) which is attenuated by inactivation of viral ribonucleotide reductase (RR) and deletion of both γ(1)34.5 genes. The cellular counterparts that can functionally substitute for viral RR and the carboxyl-terminal domain of ICP34.5 are cellular RR and the...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Petrowsky, Henrik, Roberts, Gretchen D., Kooby, David A., Burt, Bryan M., Bennett, Joseph J., Delman, Keith A., Stanziale, Stephen F., Delohery, Thomas M., Tong, William P., Federoff, Howard J., Fong, Yuman
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114433/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11435585/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.15.7050-7058.2001
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