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Functional Interaction between Fluorodeoxyuridine-Induced Cellular Alterations and Replication of a Ribonucleotide Reductase-Negative Herpes Simplex Virus

G207 is an oncolytic herpes simplex virus (HSV) which is attenuated by inactivation of viral ribonucleotide reductase (RR) and deletion of both γ(1)34.5 genes. The cellular counterparts that can functionally substitute for viral RR and the carboxyl-terminal domain of ICP34.5 are cellular RR and the...

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Vydáno v:J Virol
Hlavní autoři: Petrowsky, Henrik, Roberts, Gretchen D., Kooby, David A., Burt, Bryan M., Bennett, Joseph J., Delman, Keith A., Stanziale, Stephen F., Delohery, Thomas M., Tong, William P., Federoff, Howard J., Fong, Yuman
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114433/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11435585/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.15.7050-7058.2001
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