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Octamer-Binding Sequence Is a Key Element for the Autoregulation of Kaposi's Sarcoma-Associated Herpesvirus ORF50/Lyta Gene Expression

The expression of the Kaposi's sarcoma-associated herpesvirus (KSHV) open reading frame 50 (ORF50) protein, Lyta (lytic transactivator), marks the switch from latent KSHV infection to the lytic phase. ORF50/Lyta upregulates several target KSHV genes, such as K8 (K-bZip), K9 (vIRF1), and ORF57,...

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Autori principali: Sakakibara, Shuhei, Ueda, Keiji, Chen, Jiguo, Okuno, Toshiomi, Yamanishi, Koichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC114417/
https://ncbi.nlm.nih.gov/pubmed/11435569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.15.6894-6900.2001
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