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Octamer-Binding Sequence Is a Key Element for the Autoregulation of Kaposi's Sarcoma-Associated Herpesvirus ORF50/Lyta Gene Expression

The expression of the Kaposi's sarcoma-associated herpesvirus (KSHV) open reading frame 50 (ORF50) protein, Lyta (lytic transactivator), marks the switch from latent KSHV infection to the lytic phase. ORF50/Lyta upregulates several target KSHV genes, such as K8 (K-bZip), K9 (vIRF1), and ORF57, final...

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Sakakibara, Shuhei, Ueda, Keiji, Chen, Jiguo, Okuno, Toshiomi, Yamanishi, Koichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2001
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114417/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11435569/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.15.6894-6900.2001
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