Interleukin-12 (IL-12) and IL-18 Are Important in Innate Defense against Genital Herpes Simplex Virus Type 2 Infection in Mice but Are Not Required for the Development of Acquired Gamma Interferon-Mediated Protective Immunity

Using a combination of gene-targeted mice and neutralizing antibodies, we showed that interleukin-12 (IL-12) and IL-18 are important in the innate control of genital herpes simplex virus type 2 infection but were not found to be critical, either singly or in combination, for the development of a pro...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Harandi, Ali M., Svennerholm, Bo, Holmgren, Jan, Eriksson, Kristina
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2001
Fag:	Pathogenesis and Immunity
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114395/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11413339/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.14.6705-6709.2001
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