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Innate and Adaptive Immune Responses to Herpes Simplex Virus

Immune responses against HSV-1 and HSV-2 are complex and involve a delicate interplay between innate signaling pathways and adaptive immune responses. The innate response to HSV involves the induction of type I IFN, whose role in protection against disease is well characterized in vitro and in vivo....

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Principais autores: Karen L. Mossman, Tracy Chew, Kathryne E. Taylor
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2009-11-01
coleção:Viruses
Assuntos:
Herpes Simplex virus (HSV)
innate immunity
antiviral signaling
type I interferon (IFN)
Natural killer (NK) cells
plasmacytoid dendritic cells (pDCs)
adaptive immunity
Acesso em linha:http://www.mdpi.com/1999-4915/1/3/979/
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