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The Innate Immune Response to Herpes Simplex Virus 1 Infection Is Dampened in the Newborn Brain and Can Be Modulated by Exogenous Interferon Beta To Improve Survival

ABSTRACT Newborns are particularly susceptible to severe forms of herpes simplex virus 1 (HSV-1) infection, including encephalitis and multisystemic disseminated disease. The underlying age-dependent differences in the immune response that explain this increased susceptibility relative to the adult...

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Detalhes bibliográficos
Principais autores: Daniel Giraldo, Douglas R. Wilcox, Richard Longnecker
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020-06-01
coleção:mBio
Assuntos:
Acesso em linha:https://journals.asm.org/doi/10.1128/mBio.00921-20
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