Perforin and Fas Cytolytic Pathways Coordinately Shape the Selection and Diversity of CD8(+)-T-Cell Escape Variants of Influenza Virus

Antigenic variation is a viral strategy exploited to promote survival in the face of the host immune response and represents a major challenge for efficient vaccine development. Influenza viruses are pathogens with high transmissibility and mutation rates, enabling viral escape from immunity induced...

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Hlavní autoři: Price, Graeme E., Huang, Lei, Ou, Rong, Zhang, Menghua, Moskophidis, Demetrius
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143766/
https://ncbi.nlm.nih.gov/pubmed/15956596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.13.8545-8559.2005
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